Evaluation of Mean Thrombocyte Volume and Thrombocyte Levels in Metabolic Syndrome

Abstract

Objective: In the study, the relationship between metabolic syndrome and average thrombocyte volume and thrombocytes values was evaluated. The difference between waist circumference, arterial hypertension, HDL, triglyceride levels, thrombocyte volume and thrombocytes levels between patients with metabolic syndrome and patients in control group was investigated.

Methods: The study is a retrospective case-control study. Adult patients registered to Family Medicine Unit were retrospectively scanned between January 1, 2017 and December 1, 2020. The family medicine information system (FMIS) was utilized to assess which patients had metabolic syndrome and which patients did not. A simple random sample procedure was used to enroll 382 persons from the research population. From the data, the patients’ sociodemographic parameters, waist circumference, arterial blood pressure, HDL, triglyceride, thrombocytes and average thrombocyte volume values, documented in the research form we developed. The IBM SPSS 21.0 program was used for statistical analysis, and the statistical significance threshold was set at p<0.05.

Results: The patients in the research were 48.2 years old on average, with 61 percent of them being female. In individuals there is a weak, negative, statistically significant correlation between thrombocytes and average thrombocyte volume. It was found that the platelet value was higher in females than males. It was shown that as the level of education increases metabolic syndrome reduced. Abdominal obesity was found to be the most common metabolic syndrome component in the population with metabolic syndrome. It was determined that body mass index increased the risk of metabolic syndrome by 27.5%, triglyceride increased by 2%, fasting blood sugar by 14.9%, and platelet value increased by 1.1%.

Conclusion: Patients with low educational status and obesity should be given priority in the diagnosis of patients with metabolic syndrome who are at high risk of cardiovascular problems in primary care. However, no effect of average thrombocyte volume in predicting metabolic syndrome was found. In our study, thrombocyte value was interpreted as metabolic syndrome positively.