Unilateral periocular hemorrhage caused by flurbiprofen: A rare drug side effect

Abstract

Non-steroidal anti-inflammatory drugs are often used in various indications. The side effects of these drugs are also must well known. In this study, we aimed to present a case report of a 50-year-old female with unilateral periocular hemorrhage after taking 100 mg oral flurbiprofen. Computerized tomography and magnetic resonance imaging were performed to distinguish differential diagnosis causing periocular hemorrhage on ophthalmic examination. The absent of all kind of trauma was questioned in detail. In the imaging, only soft-tissue edema around the left eye was observed. Laboratory values were normal except a mild elevation of the lactate dehydrogenase and c-reactive protein. Symptomatic treatment was planned. In the follow-up visit; control biochemical and hematologic parameters were normal. Periocular hemorrhage was regressed. Hemorrhagic skin lesions should be kept in mind as a rare drug side effect of flurbiprofen.