Esophageal ulcer development after a single dose of Doxycycline: a case report

Authors

  • Seher Sayın Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Aile Hekimliği Anabilim Dalı, Arş. Gör., Konya
  • Ruhuşen Kutlu Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Aile Hekimliği Anabilim Dalı, Prof. Dr., Konya.
  • Serhat Sayın Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi İç Hastalıkları Anabilim Dalı, Arş. Gör., Konya.
  • Hüseyin Ataseven Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Gastroenteroloji Bölümü, Doç. Dr., Konya.

DOI:

https://doi.org/10.15511/tahd.14.03156

Keywords:

acne vulgaris, esophagus, ulcer, doxycycline

Abstract

Although it is not so frequent in medical literature, drug-induced esophageal ulcer is important due to its possible complications. Doxycycline can cause esophagial irritation if not taken with sufficient water or just before going to sleep. In this case report, a 24 year-old female patient who had been prescribed doxycyline for acne is presented. She was admitted with retrosternal pain and dysphagia which had started after taking the first oral dose of the drug. Endoscopic examination showed superficial ulcerations in the area of 2 cm of the mid esophagus. Based on the endoscopic findings, the patient was diagnosed as druginduced esophageal injury resulting from doxycycline treatment. Doxycycline treatment and oral intake were stopped. Intravenous fluid therapy, sucralfate and lansoprazole treatment were started. In the following days, the patient’s complaints disappeared gradually. As in our case, irrespective of the exposure duration, even after a single dose, esophageal ulcer may develop.

Published

2014-09-15

Issue

Section

Case Report

How to Cite

Sayın, S., Kutlu, R., Sayın, S., & Ataseven, H. (2014). Esophageal ulcer development after a single dose of Doxycycline: a case report. Demo Journal, 18(3), 156-158. https://doi.org/10.15511/tahd.14.03156