Talasemi majör, osteoporoz, osteopeni.Pseudomonas aeruginosa pneumonia as cause of persistent cough in a child with cystic fibrosis: a case report

Abstract

Cystic fibrosis (CF) is a disease which is caused by a mutation in the transmembrane conductance regulator gene, and displays autosomal recessive heredity. Cystic fibrosis trans-membrane regulator protein (CFTR) is required to regulate the components of sweat, digestive fluids, and mucus. The prevalence of the disease is estimated as 1/2500-1/3500 in the white race. But the frequency of CF is not known for our country. Cystic fibrosis occurring in childhood, is a hereditary disease that proceeds with the dysfunction of all exocrine glands. The characteristic feature of the disease is the production of abnormal secretions in sweat, salivary, tracheobronchial, colon, urogenital system and pancreatic exocrine glands. The significant clinical signs of cystic fibrosis are chronic obstructive pulmonary disease and pancreatic insufficiency symptoms. Pseudomonas aeruginosa may lead to colonization, chronic and recurrent infections in patients with CF. In this article, a 10-year-old girl with CF having persistent cough related to acute exacerbation of chronic lung infection due to Pseudomonas aeruginosa colonization, has been presented.